Causes Of Diabetes Types
The
word diabetes is common enough. Nearly everyone has heard it and you may
know someone who has it. But how many know what it is?
Diabetes is a medical condition identified by continual abnormally high
levels of glucose in the blood. It is a disease that results when either the
body fails to produce adequate insulin or the cells resist using the insulin
produced.
In
the first case (insufficient amount of insulin produced) diabetes is called
Type One. In the second instance, the condition is known as Type Two
diabetes. Type One constitutes about 7% of cases, while Type two is
responsible for 90% or more. The disease affects about 7% of the population
of the U.S., occurring more frequently among those age 60 and older.
There are other types, such as gestational diabetes that sometimes afflicts
pregnant women, and others. But they are much less common and, in some
cases, temporary.
Typical causes for either diabetes types are abnormally frequent urination,
produced by the body's attempt to clear excess glucose by elimination. As a
result, unusual thirst is common, compensated for by drinking higher than
average amounts.
Type
1 has historically been known as juvenile onset diabetes, since it affected
mostly younger people. Similarly, Type 2 was called adult onset diabetes,
since it was found mostly in older adults. In Type 1 diabetes, it's believed
that one of the primary factors
causing the disease is an autoimmune system
malfunction that affects the pancreas. Type 2 may be caused or worsened by
obesity and other factors.
Both
have genetic components as risk factors. But in either type, and regardless
of the cause, the net effect is the same: an inability to clear glucose out
of the bloodstream because of inadequate or faulty insulin production or
use.
Insulin is the hormone chiefly responsible for regulating the level of
glucose in the body. Many foods that contain carbohydrates are broken down
by digestion and produce primarily glucose. That glucose is taken up by the
body to supply the energy needed for cell repair, muscle movement and a
thousand other functions. Insulin helps the glucose make its way into the
cells.
When
insulin is produced in too low an amount, or the body's cells resist the
intake of glucose by interfering with insulin's function, diabetes is the
result. Since the pancreas produces the overwhelming majority of the body's
insulin, when some condition causes it to malfunction, diabetes can result.
The
condition, whether Type 1 or Type 2, is usually chronic. But chronic doesn't
mean that nothing can be done to minimize the effects. With proper diet and
what are today relatively simple treatments, diabetes of either type is
manageable. And the disease itself comes in a range of degrees. In some
cases, the amount of insulin produced or used is only slightly under what's
needed. In other cases, the pancreas produces almost none or the cells
resist it strongly.
Since excess glucose left in the bloodstream can lead to a range of
complications, diabetes can have a number of follow on effects. But how
severe those effects are depends on the severity of the insulin deprivation
or resistance.
Diabetes, a disease characterized by chronic high levels of glucose in the
blood, is not the major problem it once was. Prior to the end of the 19th
century, it might well have been a death sentence for many. Excess glucose
can have a number of ill effects, including poor cut healing or kidney
damage, even coma. With the advancement of monitoring and insulin delivery
methods, it's often now little more than another daily task to perform.
Though the underlying causes are not fully understood, diabetes results from
either too little insulin being produced or ineffective use of it by the
body. In Type 1 diabetes, for example, the islet cells of the pancreas fail
to produce an amount of insulin adequate to allow blood glucose to enter
cells where it's used for energy. In Type 2, the cells may resist insulin's
action, once again leaving too much glucose in the blood.
But
though they're not completely known, experts agree that the causes of
diabetes types are generally a combination of genetic predisposition and
environmental or lifestyle factors. In some cases, one or the other may
dominate. Gestational diabetes, for example, affects about 3% of pregnant
women usually from around 24-28 weeks into term. But it goes away after
birth. Type 1, on the other hand, affects mostly juveniles and is largely
genetic.
In
all cases, the symptoms are usually roughly the same: excessively frequent
urination, unquenchable thirst, sometimes accompanied by dizziness or
stomach pains. Naturally, these common symptoms can have a number of causes.
Anyone suspecting he or she has diabetes should be tested by a physician.
Those tests are simple and relatively painless, only requiring a small blood
sample. Blood glucose level is measured, with normal running around 99 mg/dL,
while diabetics have a level of 126 mg/dL or above. It may require more than
one test to confirm the disease.
Once
confirmed, regular blood glucose monitoring is a must. Fortunately, there
are today many convenient ways to do that. Testing devices the size of a
cell phone are common. A small sample of blood is smeared on a strip fed
into the instrument, which delivers a number within seconds. Some recent
devices measure glucose level through the skin using an infrared beam.
Treatments are equally easy for most diabetics. In some cases careful diet
and appropriate exercise may be enough to keep the right glucose-insulin
balance. In the usual case, insulin delivery is called for. But that too is
much easier than in generations past. Small insulin-containing pens can
deliver the exact right dose painlessly. Newer oral inhalers are on the
market that have met with success.
Though no one wants to have to deal with diabetes, managing the disease is
now easier than ever. The possible long term complications of untreated
diabetes remain what they always were. By keeping them at bay with simple
techniques, most diabetics can enjoy an active fulfilling life just as
anyone else.